Could make sense theoretically, cannabis grows different ratios and amounts of terpenes and cannabinoids in different parts of its buds.
If you sample different buds to produce a bowl, you're averaging across the flower, so you get a more average experience. If you want full consistency, grind your entire batch as soon as you get it lol, and you're getting closer to the terpene profile/%s they measured in the lab which was also produced from analysing and averaging various samples.